
#1 Hot water
The hottest new H2O trend? Hot water 😎.
After sharing Morning Water in last week’s edition, reader Sarah M. tipped me off that hot water is having a moment—backed by a spike in Google searches and TikTok creators pushing it as a metabolic hack.
This trend isn’t a new supplement or an expensive longevity protocol. It's just, er, hot water. Orrr hot water with lemon 🍋 or honey 🍯 or whatever you want to add to it 🤷♂️. I like that it's trending because it's sort of an anti-biohack hack. It’s disarmingly simple. It’s low-effort. And it’s basically free.
Worth saying: there’s very little hard science here. But proponents claim hot water can help with:
Decreasing stress levels
Flushing out toxins
Improving circulation
Reducing shivering in the cold (lol, shocker)
Relieving constipation
Supporting digestion
Annnd obviously, keeping you hydrated (another shocker).
The benefits aren't magical, but they're practical. And while most of them are based on anecdotal reports, it makes sense. Water is good for you. This is just a heated (rivalry🏒?) edition, and I’m into it.
#2 Lineage Provisions
As most 5HT readers know, I’m reallyyy into Lineage Provisions’ beef sticks. Original (Salt) is my go-to flavor, but I'm also a huge fan of the Spicy Southwest. (I know, very Texas of me 🤠.)
One of the biggest reasons I always keep these in stock is how stupidly simple the ingredients are. They’re made with 100% grass-fed beef, plus heart and liver for nutrient density, and for the flavored sticks, organic spices. That's it. No seed oils, no fillers, no preservatives, nothing weird. They taste amazing, and I really dig them.
I’m also really pumped because Lineage typically only offers 10% off, but they're giving the 5HT community an exclusive 15% off. That's rare for them, so if you've been on the fence, take a bite, and let me know what you think.
#3 Heart rate variability
Last week, I shared how my HRV tankeddd after my heart surgery—dropping from an average of ~80 pre-surgery to the low 20s.
I assumed I understood HRV well enough. High = good. Low = bad. But over the weekend, I was talking it through with a friend, and once I was pushed a bit, I realized I didn’t actually understand the concept as well as I thought 😬. So this is me owning that.
I went back and did the research. And now, I think I finally have a clearer read.
At a basic level, HRV (heart rate variability) refers to the tiny variations in time between each heartbeat. Those variations are normal—and important.
Basically, a heart that beats less consistently (more variability) is usually a good thing. It’s a bit counterintuitive, but it essentially signals your body is flexible, adaptive, and responsive to its environment.
HRV is largely controlled by your autonomic nervous system (ANS). A higher HRV ⬆️ generally means greater resilience and parasympathetic (rest-and-recover) activity. A lower HRV ⬇️ often shows up during periods of stress, inflammation, illness, poor sleep, heavy training, or recovery from procedures.
Ultimately, what matters here isn’t avoiding stress altogether—but how quickly you recover from it. As Marco Altini (really the preeminent voice on HRV) told our friends at InsideTracker, “Stress can be good, and sometimes it's essential. The point is not to avoid all stressors, but rather to put yourself in a state where you bounce back very quickly." I also like how this rando put it on Reddit:
Now, you probably don’t want your HRV to be spiking too high. In fact, mine probably was in part due to my arrhythmia. There’s a sweet spot in between that’s the goal. And you can see below, my HRV is now rising and getting back into that middle zone 2 weeks post-ablation:

It’s worth saying HRV isn’t about chasing a single “perfect number.” In fact, it’s highly individual, and what’s “good” or “bad” only makes sense relative to your own baseline. Hormones (including the menstrual cycle), age, illness, and even the seasons can influence it. It’s a finicky metric—but a useful one if you know how to read it.
Anyway, if you also thought you understood HRV… but wouldn’t volunteer to explain it in public 😆, I hope this helped.
#4 Alginic acid
I’ve had a lingering suspicion I have silent reflux, and I wanted to find a non-medication way to deal with it. So, for the past month, I’ve been testing alginic acid—a naturally occurring polysaccharide derived from brown algae (aka seaweed). And… so far, I’m into it!
If you’ve never dealt with silent reflux (also called laryngopharyngeal reflux), it’s basically acid reflux without the classic heartburn. Instead, it shows up higher in your throat. For me, that meant a sore throat when swallowing at night (especially when lying down), or waking up with throat irritation in the morning—most noticeably after red wine 🍷.
After doing a bunch of research, I added Esophageal Guardian, which contains alginic acid and potassium bicarbonate, to my evening supplement stack. I chew two tablets ~30 minutes before bed. Fair warning: the taste is… strong and awfully sticky. Buuut all the alternatives sound way more gross (the most famous one is Reflux Gourmet, a spoonful of gel which comes in Mint Chocolate and Vanilla Caramel—not flavors I want before bed). Anyway, I just follow it up with my oral care routine 🤷♂️.
Here’s what makes alginic acid interesting: Unlike PPIs or H2 blockers, it doesn’t suppress stomach acid. Instead, when it hits stomach acid, it forms a floating gel “raft” that sits on top of your stomach contents. That raft acts as a physical barrier, preventing acid and pepsin from splashing up into the esophagus while you’re lying down. Think of it like a dam in the river.
Four weeks in, I haven't woken up with a sore throat. There’s no more burning feeling at night. No irritation in the morning. So in that sense, I think it really works. I was half hoping it would also help my PVCs, since there’s some connection between reflux and heart health ❤️. It didn’t, but that’s fine. So far, it’s done exactly what it was designed to do.
Would I take it every night forever? IDKID. My plan is to use it for another month, then shift to a situational tool—late dinners, travel, heavier meals, red wine—rather than a daily ritual. It’s not a miracle. But for silent reflux, I think it’s been surprisingly effective.
#5 Stewery weather

If ever there was a time for a stewery, it’s now. It literally snowed in Florida last week!
If anyone opens one of these, hit me up. I’ll be first in line for a soup flight.
⚡ Neural hacks
Directions: Copy and paste the below prompt into your AI platform of choice to blend up your perfect smoothie recipe.
Act as a thoughtful, evidence-based nutrition guide with a busy schedule. Create a smoothie recipe tailored to my health goals and preferences.
Use whole-food ingredients where possible, and prioritize factors most relevant to my stated goal. Limit the recipe to 10 ingredients or fewer (excluding water/ice).
Provide:
– A complete smoothie recipe with measurements
– A brief explanation of what each ingredient supports
– One optional “upgrade” ingredient and why it helps
Primary health goal (choose 1–2):
– Stable energy
– Blood sugar balance
– Gut health
– Hormone support
– Muscle recovery
– Brain focus
– Anti-inflammatory support
– Weight maintenance
Secondary goal (optional):
– e.g., digestion, skin, stress, endurance
Must-have ingredients:
–
Ingredients to avoid:
–
Macro balance preference:
– Protein: higher / moderate
– Fat: lower / moderate / higher
– Fiber: lower / moderate / higher
Sweetness preference:
– Not sweet / lightly sweet / naturally sweet
When I’ll drink it:
– Morning / post-workout / afternoon / evening
Anything else to consider:
– Sensitive digestion, reflux, training load, meds, travel, etc.
🍿 Brain snacks
Lotus Health enters the AI doctor space with $35M in funding.
Carbon Health files for bankruptcy. I think it’s just some capital restructuring, but still–did not have that on my 2026 bingo card.
“Sexy” allergy care is a thing… and as someone with chronic allergies, I’m into it! 😆 Thanks for sharing, Catarina D.!
SuppCo plans to launch its own research into supplements. Pretty neat.
Midi announces $100M fundraise and a rumored $1B+ valuation! Congrats to Joanna and the whole team. 👏
Pelvic floor & whole-body physical therapy brand, Origin, announces Series B. 💰
WellTheory launches a postpartum-focused program for women with autoimmune disease.
Hims' new SuperBowl ad is prettyyy aggressive. Plan to share a roundup of my fave health commercials in next week’s edition!
Fitbit co-founder James Park launches Luffu, an app that proactively watches over your family’s health and safety. Waitlist only right now.
Peloton lays off 11% of its workforce. 😔
Eric Topol says he “finally agrees with Bryan Johnson” on the recent AG1 research.
WHOOP got banned during the Australian Open…and CEO Will Ahmed overnighted more discreet ones, lol.
This video on the history of weightlifting in the US from the NYT is nicely done. 👌
The NYT also reports intermittent fasting data gets less convincing when studies are better and bigger. 😬
CB Insights published its 2025 State of Digital Health Report featuring 3x as many unicorns 🦄 as 2024.
Peter Attia is in the Epstein files. His response was disappointing IMO and there’s been a LOT of blowback. 😔
Oh—and our 5HT+ Slack channel was into this article in The Cut about the rise of “trimester zero.” Thanks for sharing, Abigail B.!
Most clicked last week: Seems everyone’s thirsty… y’all loved Morning Water! (Remember to use “5HT” at checkout to get 10% off.)
Want in on 5HT+? Two referrals get you in. Share your unique code with that one coworker who’s always drinking their smoothie on Zoom or the one friend who’s always sharing their HRV level, and join the chat. → {{ rp_refer_url }}
👋 Who are you again? I’m Derek Flanzraich—founder of two venture-backed startups in Greatist (👍) and Ness (👎). I’ve worked with brands like GoodRx, Parsley, Midi, Ro, NOCD, and Peloton. I now run Healthyish Content, a premium health content & SEO agency (among other things).
Every Thursday, I share 5 health things I feel strongly about so you can live healthyish. (Disclaimer: I’m more your friend with health benefits. None of this is medical advice.)
And oh, you also feel strongly about some health things? Hit reply—I’d love to hear it.



